Peer-reviewed by 2 reviewers with median rating of 14.5/20. Review process was triple-blinded.
Round 1 (14.5/20)
Conceptual advance and Impact6
please add a background control for in-situ hybridization (figure a)
Conceptual advance and Impact8
Nice work, and the idea is needed to be continued.
Can be accepted, with minor remarks answering.
Results & Discussion
What were the locations in planarian body of that numeral injections?? Please answer in the text
Don't you think that these abnormal tissues ( you show on Figure) can be somehow related to that injections?
Also - in last row of the first paragraf - it is not a mistake "yki"??? shoul be yorkie or not??
the functional study of yorkie, -last two letter should be in italic too! fourth row from the bottom