Peer-reviewed by 2 reviewers with median rating of 11.5/20. Review process was triple-blinded.
Round 1 (11.5/20)
Round 2 (11.5/20)
Conceptual advance and Impact6
The abstract should include that the complex purification was with TAP-tag and the co-immunoprecipitation is under overexpressing conditions.
The conclusion should also include that in both experiments were done under overexpression conditions (in the case of MS also with the TAP-LL5beta vector).
Conceptual advance and Impact5.5
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1A: please include which peptides of LL5BIP have been detected. 1B: It appears that the co-IP has only been done once. I would like to at least see evidence that this has been repeated multiple time; ideally a quantification of several IP repeats would be good.