Peer-reviewed by 2 reviewers with median rating of 8/20. Review process was triple-blinded.
Round 1 (8/20)
Round 2 (8/20)
Conceptual advance and Impact3
This is a well conducted experiment with very significant results, which nevertheless lacks some novelty as resolvins and related molecules have been demonstrated to regulate pain conditions. Related to this, recent publications are missing in the text.
Change "in a mouse model of peripheral nerve injury", to a proper keyword.
The legend is incomplete, data about deviations and statistics are missing.
There is a recent review from Lim et al 2015 that should be included as they review the roles of resolvins in the resolution of pain
Results & Discussion
The text is incomplete
Please comment about the results using DHA/EPA plus aspirin. The lack of difference in this group when compared to DHA/EPA gives any information about the possible mechanism of action?
You can use this section to conjeture mechanism of action, specially considering there is no change in the effect of DHA/EPA with or without aspirin
The more recent reference is from 2013, there is no recent data about this topic (see above for a suggested review)